I am tempted to just put in here a whole game because I think 99% of the characters in this game are annoying as shit but, okay, just one.
I'll have to say... Hope. From Final Fantasy XIII.
I spent 25 hours in the game trying not to throw my damn controller at my TV every time Hope comes on. Now before fanboys try to burn me to the ground and defend the little shit, yes I know he's depressed, his mum died, his dad doesn't love him and everyone's out to get him, yes I get it.
What I don't like about Hope is how he deals with it. His self-entitlement gets seriously annoying when you have to put up with it for hours.
In his defense though, I heard he gets better further into the game. That he finally mans up in the end. Well, too bad the game can't hold my attention for more than an hour without lulling me to sleep for me to see that happen. But that is something best saved for another discussion.